I was thinking, something in my audio system apparently didn't make it into Yosemite. So I went hunting for it. It was ProTools. ProTools 9 to be exact.
I had bought into having it as a universal, blah blah a few years back, didn't end up using it really.. but it had put a bunch of crap on my drive that's been with me since. There was no uninstall available, so I had to manually remove every one of these files from my Library, as per a list some kind soul posted on the web.. and there were a lot of them!
I didn't even know if it would work but it did, the message and subsequent reload no longer occur! Where I found it was in the Audio MIDI Setup app. I repaired the permissions a lot through all this, one must.
I swear DP 9 was snappier for a while after I did all this, but then I tried to automate the pitch on a guitar note and it crashed. Guess I need to go back to 8.. again..

DP11, 2019 16-Core Mac Pro, OS 14 Sonoma , 64GB RAM. RME HDSPe MADI FX to SSL Alphalink to SSL Matrix console, and multiple digital sub consoles. UAD Quad PCIe. Outboard stuff.