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EDIT >>> My main complaint about the Track Selector changes turn out to have been a false alarm. It is not an issue, as Daveyboy has so wisely corrected further down in this thread. MOTU did allow for the DP5 style of the Track Selector in the preferences: Preferences > Edit Windows > Always opens the edit window's Track Selector
I'm so sorry to have cried wolf about this particular thing. I should have explored further before posting this issue.


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As much as I didn't want to have to contribute to the complaints about DP6, I'm afraid I do have several beefs and disappointments of my own.

There are DEFINITELY some great new additions, which will aid in a more efficient workflow. Unfortunately, there are other changes and additions that I believe are going to hinder workflow, and some GUI aspects which are very distracting and may also impede workflow.
Let me start by posting an image of a simple project in DP5.
Please note the following:
a) The Track Selector section at the left side of the graphic editor window is a part of the graphic editor window. This Track Selector list relates to the graphic editor and therefore remains connected to the graphic editor.
b) The background of the graphic editor is light grey, and the contrast between the "white keys" and the darker grey "black keys" is very soft and unobtrusive.
(c) In the tracks window, the blocks have the colour of the track in the form of a little sliver of color at the top of the track.
(d) The consolidated window tabs are smaller, less wide, and justified to the right of the layout, so that the presence of the tabs and the words on them do not conflict with the legibility of the text below them in the tracks window.

Now let's take a look at the same project in DP6.
Please note the following:
(a) When you click on the Track Selector button at the bottom left of the graphic editor window, the track selector now opens up in a separate consolidated window...
EDIT >>> But this is only a default preference which can be changed. As noted above, this is no longer an issue. Preferences > Edit Windows will allow you the option to have the DP5 style Track Selector. Thanks daveyboy!!
(b) The background of the editor window is white with grey lines denoting the "black keys". The contrast is now over the top and the horizontal lines seem more distracting. This is much more noticeable, again, when you are looking at a much bigger section of the edit window on a big screen... it doesn't look so bad in this screen capture. I am not sure I mind the white so much, but I would like the ability to either lighten the darker grey, or darken the light areas so that the contrast is not so stark.
(c) In the tracks window the blocks are now fully coloured in a pastel version of the main track colour. To my eyes this is distracting and a little tacky looking. I would like some options with regards to how the tracks in the tracks window are viewed. I would rather see them more like they were before, although it might be nice for the sliver of colour on top to utilize these more muted pastel colours of DP6. Options would be great.
(d) The consolidated window tabs are now bigger, and wider, and justify to the left. Admittedly, there are now items below those tabs (on both the right and left side) so one side or the other might not be more conflicting than the other. But the fact that they are bigger and stretch longer, means that their presence is less easy to ignore.

Other initial discoveries included:
(1) So far, I haven't found DP6 to be any more snappy than DP5, and noticed no improvements in CPU usage. With just a couple of PLAY instruments loaded, and pre-rendering supposedly turned on, I still run into the red as much or more than the same project opened in DP5. I am not sure if I need to upgrade my OS version to take better advantage of pre-rendering efficiencies. Perhaps efficiencies will be noted more with plugins than with VIs, I don't know yet.
(2) SoundToys is not working. The knobs do not respond properly. I haven't checked all my plugins, but this is one that I use quite a lot. Perhaps the problem will suddenly disappear, as some others have reported... but that hasn't happened yet.
(3) I have to agree with others that the whiteness of the design is definitely causes an immediate increase in eye strain. I had to adjust the contrast of my monitor to cut it down a little. I think I like it a bit lighter than it was in DP5, but there should definitely be an option to lighten and darken the GUI without having to adjust your monitor.
(3) To end on a more positive note, there are lots of great improvements, which include the presence of a drop down list that shows up on any of your VIs revealing other VIs that are currently loaded. So in order to bring up a VI window that is hidden behind another you simply select it in the drop down list on the frontmost VI. Very easy and swift.

That's my initial report. Sorry it wasn't more glowing. I think I am going back to DP5 until some of this stuff is sorted out. It seems, so far, that both versions can live harmoniously on my system.