I have a dilemma and am pushing a bit above my weight class in this matter. I have recently been upgrading my studio and sprung for a newer Mac. Specifically, I purchased a 2018 Mac mini with 64 GB RAM, but only a 500GB internal SSD. I intentionally stayed away from the latest M1 Macs since it seems that all my music software including DP and Waves will not be compatible for quite a while. I am now running the latest version of DP and Mach 5.
The problem is that I have 2 large Seagate Ironwolf 12GB 7200 rpm spinners and I am not sure whether to format these in APFS or HFS+ Journaled format. I have large amounts of old DP/Audio files. I have been wanting to save these DP Audio files/Samples/Miscellaneous in separate partitions on one large drive and then back all this one drive up via straight RAID 1 back-up to a 2nd 12 GB Seagate drive. This all made sense to me when I was thinking of ways to save all my audio and computer files together and then back things up in a straightforward manner. Now I am seeing that it is better to have the DP files on the boot drive which for me is a no go given my small 500GB boot drive. Besides, when I used Apple Time Machine in the past, my back-ups all became incredibly large compared to the source material in a very short amount of time to not make them practical for me.
Now I hear that there are not only partitions, but volumes with AFSP among many other things. Besides all that, varied internet sources state that AFSP does not work well with old (pre 2017) Mac volumes/files and that HFS+ is recommended for the older spinners like my Seagate drives. Moreover, Seagate themselves seem to recommend HFS+ Journalled. Help??
If I didn't have so many old DP audio files/Mac files, I think my decision would have been much clearer, thus my need for lots of storage space and back-up. From what I now know, there is much change that is "afoot" in the Mac related music world as of late. Down the road, I will likely get more SSD's for samples and current DP files when I get some more money, but that may be not for a awhile unless my wife has a change of heart!?

Thanks in advance for any help cleaning up my mess.
Cheers!
Dave from frostbitten Edmonton in the far reaches of Canada.