I hope someone can help me with this. I have a 424 system (2408-24i/o 1-24i/o 2) and am having the problem that all of my levels of inputs are showing up great in my LED meters on the units themselves, but nothing is coming through to record enabled inputs in the software I am using (Logic 8 and Live

I have checked my MOTU PCI audio Set Up and all my inputs are enabled as well as selected outputs to my monitoring system. I can see the meters working perfectly in my PCI CueMix Console (all mutes are off).
There is no signal whatsoever that is passing through to my software. Just dead.
I know all the hardware works as I had everything up and running perfectly in 10.4. I just wiped my entire drive clean with a format and clean installed 10.5, reinstalled all the latest drivers from the MOTU site and here I am writing this blog. Nothing else changed but that.
Any ideas what I might be missing in this?
Thanks so much in advance for any quick help on this.
nz
10.5.6
G5 Dual 2.7
2408
2-24i/os