Hoping someone here might have had a similar situation to me, becuase i keep posting to the techlinks support area at MOTU and simply get nil response.
Anyhow - as a start, the overview is, My 2408MkIII cannot be seen by my 424 PCI card (not PCIe).
I have done numerous tests on my system, of which i have dual boot 32bit & 64 Bit OS's to see if 64bit drivers make a difference, but NO.
What i did do was install it on an friends older PC (Dual Xeon) - and it worked first go.
You would deduce a hardware conflict, but NO, Windows device manager shows no conflict what so ever - the 424 installs without a hitch in 32 & 64 bit version.
HOWEVER - what i did notice was that on my friends PC (where it worked) after the 3 main PCI drivers were installed (AUDIO-WAVE-GSIF) his PC installed about another 5 drivers i rekon? it was too fast to see in the little bubble near the new hardware icon, BUT - i did see stuff like "streaming clock" or "clock system", things like that.
I never saw any of this on any of my installs (32bit of 64 bit). I can only assume that these sync/clock drivers are what is stopping my 2408 locking to the 424 PCI card.
I have tried rolling back to earlier drivers (some suggest this works on this forum), but no affect.
Have updated the BIOS on my motherboard, disabled just about all integarated perhipherals (except USB so my KB & mouse will work).
I also completely blew away both versions of XP re-installed fresh and went straight for MOTU drivers, no Motherboard drivers no video drivers, just XP then MOTU, still no joy.
ENVIROMENTALS:
Below is alist of the enviroment variables for anyone who might be able to help me.
Primary OS (XP SP3 x86) - 64 bit version is only for driver testing
Running on board RAID (From Intel Mem controller)
Intel Core 2 Quad 2.8G
Gigabyte EP45-DS4P (Intel P45 Chipset - Intel Mem controller ICH10R)
4x1 Gig OCZ RAM
Sapphire HD4850 Vid Card
Motherboard only has 1 PCI slot, so i cant move it around to force a hardware update

Thanks again contributors, i hope there is someone out there that can shed light on this bloody frustrating situation.
-Garron
PS: Forgot to add that my card is a PCI (not X or e) card, i think it is the early one. It has only 1 slot/cut in the PCB that goes in to the PCI slot, AND it has 2 green wires that are running from the top of the 424 board to the bottom. I can only assume that my MB which has a PCI compliant slot is actually a 5Volt slot, meaning my card should work ? right?