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Just had a weird one with a three chunk session.

Working with three songs.
Each had various instantiations of KontaKt 5 (latest version)
Keyscape on one.

All was well and I was switching back and forth.
Out of the blue, switching to another chunk just gave the beach ball.

I had to force quit and reload.
The saved chunk came back fine, but trying to switch to the other chunks resulted in the spinning beach ball.
No way I could access them.

I openend a new project and was able to load the missing two.
A major sigh of relief!

First time in a long time that DP has scared me.

I`ve had an issue similar to that. It`d get the beachball going forever until it would finally open. If I recall trashed the DP preferences and the problem got fixed. Do a backup of your pref and try a clean one