MOTUnation.com

My experience:

I connected my Ultralite-mk3 Hybrid to a USB 2.0 port when I got it. For some reason I connected all devices again to my machine, and the Motu got attached to a USB 3.0 port. Problems started from that point: no sound, BSOD's, DAW hanging, etc. I read this post, switched the sound interface back to a 2.0 port, and: problems gone !

For anybody facing Ultralite Hybrid freezes, no sound or high pitch issues with Windows 7, try disabling xHCI (USB 3.0 controller) in the BIOS - even tho you're using USB 2.0 ports. That or install Windows 8. None of these solutions are entirely satisfying to me but at least it's fixing the interface issues.