I've had this problem for a long time now. It's not crippling and i've been too busy to really try and solve it, but now I do have some time on my hands.. and I just. can't. figure it out..

Please read through this.. i'm sorry it's lengthy.. but I want to be as clear as I can.
I'll try to explain as clearly as possible.
Basically, I get an audio dropout about once every few hours. Sometimes a lot, some times once a day, sometimes not at all (in a day). But it feels like some one basically pushes a Mute button on and off for about a second. As in, I've heard sometimes with MIDI it will drop out but then when it comes back, it plays the notes really fast, jumbled together. But this, even with MIDI, continues playing the notes but the audio just gets temporarily muted.. This happens to both recorded MIDI (playing back) as well as recorded audio (playing back).
My setup briefly:
Main Mac Pro - dual core, 10.6.8, DP7.24, VEP 5 (latest), Ableton Live (Rewire), PCI-424
"VEP" Slave Mac Pro - Dual Core, 10.6.8, VEP 5 (latest), PCI-424
Slave PC - uses VSTACK - really only used for old sample libraries.. (rarely used)
I have a 2408 MKIII as my "Main" 2408. Then I have 2 other 2408's connected to my Main Mac that handle "Piped" audio via ADAT from my Slave Mac/PC. Although I don't really use them too much now since I got VE Pro.. and all audio is handled over a LAN cable.. what a waste of $$ haha
I then send audio from my MKIII via ADAT to my O2R96. (I use to mix not this console, but now it just sits there routing audio, and I mix in the box.) O2R to speakers.
Here's the interesting part that may lead some of you to a diagnosis:
I route my DP Video Audio (Dialog on Left, Temp music Right) out of a little M-audio (usb) Fast track. It goes straight to my O2R, to two channels (L/R) that I can then mute when I want. THIS AUDIO DOES NOT DROP OUT! this is what perplexes me. The audio from my MKIII drops, but the dialog will stay on.
Secondly, When I'm recording something, It goes from my Symphony IO to my 2408 (via ADAT) into DP. I've experienced that when the audio drops out, it also drops the audio that is being recorded as it's being recorded. HOWEVER, when I go back to the recorded track.. THERE'S NO DROP OUT! as in.. it was recorded fine.. but some how, the audio dropped out (post fader?)
Trust me, I've tried every setting there is possible. There's no CPU Spikes, I have plenty of RAM (and yes, I've swapped them all out to ensure no bad RAM), I've tried all the "Memory allocations" possible, reformatted drives, reinstalled everything, dumped prefs. you name it. I've even had DP run just a single instrument, and sure enough, after a few hours of randomly playing, it dropped out briefly. So it (To me) doesn't seem like a software issue .. like maybe a faulty hardware.. but I don't really know where to start. any thoughts on how to trouble shoot hardware faults?
Although please give me any suggestions you may think of, even software related, I'm willing to try anything at this point.
Has anyone experienced this before? Mostly all the threads I read about dropouts are due to either a) user error or b) a CPU/ RAM error. This is neither. (I hope)
But other than that pesky dropout, everything works perfectly in my setup! It's just embarrassing when you have a professional studio, doing some major recording/TV shows and when you're recording a top paid player and he messes up because the music cuts out for a second... well.. you can see my frustration. (Not to mention printing a long cue, and before the end, it cuts out! AHH!!!)
Anyways, I'm breathing.. staying calm..

Thanks everyone!
~Marc