MOTUnation.com

That's bad news. I tried to run the MOTU class compliant as you wrote. And I installed the new Monterey update. But the problem still occurs and MOTU support didn't write back for a week or longer. I don't know what to do. Waiting? Buying another interface?

Audio usually works the 1st time, but will not work the 2nd time, whether it's the same file or the next one. Whether I click on it in Finder, Keynote, Safari.... I hear little click and then total drop out. The only way I can get it back is If I click off the file and click on a window, another fi...

I really hope that someone finds out what the problem might be. It must have to do with thunderbolt management or something like that. I wish you all the best for your presentation. Couldn't you use another system (computer and/or interface)?

I have exactly the same problem with my Ultralite MK4. It started after I installed macOS Monterey. Audio cracks, drops out or stutters – especially during streaming as YouTube but also while using apps as FinalCut Pro or Ableton Live.