My experience:
I connected my Ultralite-mk3 Hybrid to a USB 2.0 port when I got it. For some reason I connected all devices again to my machine, and the Motu got attached to a USB 3.0 port. Problems started from that point: no sound, BSOD's, DAW hanging, etc. I read this post, switched the sound interface back to a 2.0 port, and: problems gone !
UltraLite Mk3 Hybrid, no sound
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Discussion related to installation, configuration and use of MOTU hardware such as MIDI interfaces, audio interfaces, etc. with Windows
Discussion related to installation, configuration and use of MOTU hardware such as MIDI interfaces, audio interfaces, etc. with Windows
Re: UltraLite Mk3 Hybrid, no sound
For anybody facing Ultralite Hybrid freezes, no sound or high pitch issues with Windows 7, try disabling xHCI (USB 3.0 controller) in the BIOS - even tho you're using USB 2.0 ports. That or install Windows 8. None of these solutions are entirely satisfying to me but at least it's fixing the interface issues.